Frontiers in Molecular Biosciences

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PMC链接：http://www.ncbi.nlm.nih.gov/nlmcatalog?term=2296-889X%5BISSN%5D

当代生命科学的许多研究致力于分子尺度上对生物过程的理解，特别是细胞效应因子(包括蛋白质)水平的动态变化、修饰和相互作用。分子生物科学前沿为基础研究和应用研究提供了一个国际出版平台;我们鼓励在生物学的成熟和新兴领域做出贡献。为此，该杂志借鉴了结构生物学、酶学、生物化学和生物物理学等经验学科，利用了技术进步，使代谢组学和蛋白质组学测量能够大规模并行进行，并开发了强大和创新的计算生物学策略。我们还认识到医学和技术的影响，欢迎在分子遗传学、分子诊断和治疗学以及纳米技术方面的研究。除了有趣的新发现、新技术和新应用，分子生物科学前沿还将考虑新的可测试假设，以激发不同的观点和促进科学对话。有机硅、体外和体内方法的整合将有益于生命科学各个领域的努力。我们的最终目标是全面阐明调控蛋白质、核酸、碳水化合物、脂类和小代谢产物的分子机制。

Much of contemporary investigation in the life sciences is devoted to the molecular-scale understanding of biological processes — in particular, dynamic alterations in the levels, modifications, and interactions of cellular effectors, including proteins. Frontiers in Molecular Biosciences offers an international publication platform for basic as well as applied research; we encourage contributions spanning both established and emerging areas of biology.To this end, the journal draws from empirical disciplines such as structural biology, enzymology, biochemistry, and biophysics, capitalizing as well on the technological advancements that have enabled metabolomics and proteomics measurements in massively parallel throughput, and the development of robust and innovative computational biology strategies. We also recognize influences from medicine and technology, welcoming studies in molecular genetics, molecular diagnostics and therapeutics, and nanotechnology.In addition to interesting new findings, techniques, and applications, Frontiers in Molecular Biosciences will consider new testable hypotheses to inspire different perspectives and stimulate scientific dialogue. The integration of in silico, in vitro, and in vivo approaches will benefit endeavors across all domains of the life sciences.Our ultimate objective is the comprehensive illustration of the molecular mechanisms regulating proteins, nucleic acids, carbohydrates, lipids, and small metabolites in organisms across all branches of life.