Metallomics

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官方网站：http://pubs.rsc.org/en/journals/journalissues/mt

投稿网址：http://mc.manuscriptcentral.com/mt

PMC链接：http://www.ncbi.nlm.nih.gov/nlmcatalog?term=1756-5901%5BISSN%5D

金属组学发表前沿研究，旨在阐明金属和金属化合物在生物系统中的识别、分布、动力学、作用和影响。针对细胞、组织、有机体和各种环境生态位中这些无机元素的“什么、在哪里、何时、如何和为什么”的研究是受欢迎的，特别是那些采用来自分析、生物无机、医学、环境、生物物理、细胞生物学、植物生物学和化学生物学社区的多学科方法的研究。我们特别感兴趣的是那些增强我们对金属依赖生命过程的分子机制的化学和/或物理理解的文章，以及那些探索金属组学和其他组学方法之间的共同空间的文章，以揭示对生物过程的新见解。在2019年我们庆祝成立10周年之际，金属组学试图将自己定位于分析化学前沿，这些进展注定会阐明生物系统的巨大复杂性。因此，我们特别欢迎那些概述尖端分析技术的论文，例如在发展和应用强大的新成像、光谱和质谱方法方面。还强烈鼓励对复杂系统或作为微环境功能的金属形态、贩运和动力学的新见解的工作。研究金属依赖过程与机体健康或疾病相关的系统级反应之间的相互联系也受到强烈鼓励，例如，研究化学暴露对金属稳态的影响或金属药物对细胞过程的影响。作者被要求使用“对金属组学的意义”的声明，在提交所有手稿时要求，作为一种机制，以突出这些跨学科的进展，在生物学和金属组学社区的意义。

Metallomics publishes cutting-edge investigations aimed at elucidating the identification, distribution, dynamics, role and impact of metals and metalloids in biological systems. Studies that address the “what, where, when, how and why” of these inorganic elements in cells, tissues, organisms, and various environmental niches are welcome, especially those employing multidisciplinary approaches drawn from the analytical, bioinorganic, medicinal, environmental, biophysical, cell biology, plant biology and chemical biology communities. We are particularly interested in articles that enhance our chemical and/or physical understanding of the molecular mechanisms of metal-dependent life processes, and those that probe the common space between metallomics and other ‘omics approaches to uncover new insights into biological processes.As we celebrate our 10-year anniversary in 2019, Metallomics seeks to position itself at the forefront of those advances in analytical chemistry destined to clarify the enormous complexity of biological systems. As such, we particularly welcome those papers that outline cutting-edge analytical technologies, e.g., in the development and application of powerful new imaging, spectroscopic and mass spectrometric modalities. Work that describes new insights into metal speciation, trafficking and dynamics in complex systems or as a function of microenvironment are also strongly encouraged. Studies that examine the interconnectivity of metal-dependent processes with systems level responses relevant to organismal health or disease are also strongly encouraged, for example those that probe the effect of chemical exposure on metal homeostasis or the impact of metal-based drugs on cellular processes.Authors are asked to use the Statement on the “Significance to Metallomics”, required upon submission of all manuscripts, as a mechanism to highlight these interdisciplinary advances of significance to the metals in biology and metallomics communities.