Bioanalysis

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对生物样品中的外源生物和生物制剂进行选择性、敏感性和可重复性分析，从而获得可靠的数据，这是每一个成功的药物开发项目的基础和关键部分。同样的原则也可以应用于许多其他领域的研究，如法医学、毒理学和体育兴奋剂检测。《生物分析》领域结合了复杂的技术，将样品制备和先进的分离技术与MS和NMR检测系统、自动化和机器人技术相结合。监管机构制定的有关方法开发和验证的标准越来越多地界定了速度和质量之间的界限。《生物分析》是一门进步的学科，未来将有许多令人兴奋的机会进一步减少样本量、分析成本和环境影响，以及提高灵敏度、特异性、准确性、效率、分析吞吐量、数据质量、数据处理和处理。《生物分析》杂志侧重于检测或定量研究人类或动物生物样品中分析物的技术和方法。生物分析鼓励提交描述前瞻性应用的文章，包括生物传感器、微流体、微型化分析设备和新的连字符和多维技术。生物分析以简洁、一目了然的文章格式提供基本信息。该领域的关键进展由国际专家进行报告和分析，为现代生物分析学家提供了一个权威而又容易接近的论坛。主要的主题包括：分析物提取和样品制备，包括微取样色谱与分离科学MS、NMR等关键检测方法，包括配体结合检测药物和代谢物分析生物标志物检测、诊断检测和检测试剂盒方法开发和验证方法创新的生物分析方法和新的仪器设备实验室自动化及效率规管及遵从问题数据处理及管理

Reliable data obtained from selective, sensitive and reproducible analysis of xenobiotics and biotics in biological samples is a fundamental and crucial part of every successful drug development program. The same principles can also apply to many other areas of research such as forensic science, toxicology and sports doping testing.The bioanalytical field incorporates sophisticated techniques linking sample preparation and advanced separations with MS and NMR detection systems, automation and robotics. Standards set by regulatory bodies regarding method development and validation increasingly define the boundaries between speed and quality.Bioanalysis is a progressive discipline for which the future holds many exciting opportunities to further reduce sample volumes, analysis cost and environmental impact, as well as to improve sensitivity, specificity, accuracy, efficiency, assay throughput, data quality, data handling and processing. The journal Bioanalysis focuses on the techniques and methods used for the detection or quantitative study of analytes in human or animal biological samples. Bioanalysis encourages the submission of articles describing forward-looking applications, including biosensors, microfluidics, miniaturized analytical devices, and new hyphenated and multi-dimensional techniques.Bioanalysis delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for the modern bioanalyst.Principal themes include:Analyte extraction and sample preparation, including microsamplingChromatography and separation sciencesMS, NMR and other key detection methods, including ligand binding assaysDrug and metabolite assaysBiomarker assays, diagnostic assays and test kitsMethod development and validation approachesInnovative bioanalytical methods and new instrumentation and equipmentLaboratory automation and efficiencyRegulatory and compliance issuesData processing and management