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该杂志邀请评论关于化学物质与生物系统相互作用的原始论文。药理学和治疗学的所有方面都是适当的，但是没有剂量反应或机制研究的描述性病例报告是不能接受的。只有在提供数据表明使用新方法获得了新的或更可靠的药理信息时，才会审查主要涉及新方法的手稿。
The Journal invites for review original papers dealing with interactions of chemicals with biological systems. All aspects of pharmacology and therapeutics are appropriate, but descriptive case reports without dose-response or mechanistic studies are not acceptable. Manuscripts dealing primarily with new methods will be reviewed only if data are presented showing that new or more reliable pharmacological information has been obtained with their use.
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