Macroheterocycles

Macroheterocycles期刊基本信息

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PMC链接:http://www.ncbi.nlm.nih.gov/nlmcatalog?term=1998-9539%5BISSN%5D

Macroheterocycles中文简介

讨论了含硫大杂环化合物的合成方法、结构和光谱特征。以α,_-二卤代烷与碱α,_-烷二硫醇反应,合成了含2-6个硫原子的12-42元大杂环。通过芳香族1,2-二硫醇或2-巯基酚与脂肪族α-二卤代衍生物的反应,制备了含硫和氧原子的氧杂硫大环烷烃。硫大环烷烃的合成包括二甲醚或α,_烷二羧酸二氯化物与α,_烷二胺的反应,然后用LiAlh4或B2H6还原大杂环二胺。以二羧酸二氯化物与α,_-恶烷二胺反应,以及氯磺酰-β-内酰胺与乙二醇反应制备了氧杂氮杂大环烷,双(溴甲基)取代芳烃与双(巯基甲基)苯的反应是合成低聚噻环烷的一般途径。以2,6-双(溴甲基)吡啶与α,_-烷烃二硫醇反应制备了含硫环吡啶衍生物。对于含有一个、两个或多个噻吩环的大环化合物的合成,基于-噻吩烷羧酸氯化物的分子内和分子间酰化、2,5-双(碳烷氧基烷基)噻吩的酰偶姻缩合和-卤代烷基取代的噻吩β-酮酯的分子内烷基化的一些步骤。研究了含二硫化物和多硫化物的大杂环化合物的合成路线。合成过程中,均三甲苯或1,3-二甲氧基苯与二硫二氯化物或二硫二氯化物硫化,并氧化二硫醇,以1,3,5-三(巯基烷基)苯与三(溴代烷基)-甲烷或L,3,5-三[4-(巯基甲基)苯基]-苯的反应为基础,合成了双和三丙烯基环化合物。以1,3,5-三-[4-(溴甲基)苯基]苯为原料,研究了含硅、碲或铁的含硫大杂环化合物的合成方法,并用X射线衍射、核磁共振、红外光谱、紫外光谱等分析结果,讨论了含硫大杂环化合物的结构及其导电性和磁性。

Macroheterocycles英文简介

Synthetic methods for, and structural and spectroscopic characteristics of sulfur-containing macroheterocycles are discussed. The synthesis of oligothiamacrocycloalkanes is based on the reaction of α, ò-dihaloalkanes with alkali α,ò-alkanedithiolates to form 12-42-membered macroheterocycles with 2-6 sulfur atoms in the ring. Oxathiamacrocycloalkanes containing sulfur and oxygen atoms in the ring have been prepared by reaction of aromatic 1,2-dithiols or 2-mercaptophenols with aliphatic α-ò-dihalo derivatives. The synthesis of thiamacrocycloalkanes involves the reaction of dimethyl ethers or α,ò-alkanedicarboxylic acid dichlorides with α,ò-alkanediamines followed by reduction of the macroheterocyclic diamides with LiAlH4 or B2H6. Oxathiaazamacrocycloalkanes have been prepared in a similar way by reaction of dicarboxylic acid dichlorides with α,ò-oxaalkanediamines as well as by reaction of chlorosulfonyl-β-lactams with glycols.A general synthetic route to oligothiacyclophanes is the reaction of bis-(bromomethyl) substituted arenes with bis-(mercaptomethyl)benzenes. Analogously, sulfur-containing cyclopyridinophanes have been prepared by reaction of 2,6-bis(bromomethyl)pyridine with α,ò-alkanedithiols. For the synthesis of macrocyclic compounds containing one, two, or several thiophene rings, some procedures based on intra-and intermolecular acylation of ò-thienylalkanecarboxylic acid chlorides, acyloin condensation of 2,5-bis(carbalkoxyalkyl)thiophenes, and intramolecular alkylation of ò-haloalkyl substituted β-keto esters of the thiophene series have been developed.Synthetic routes to macroheterocycles containing di-and polysulfide groups are discussed. The synthesis involves sulfurization of mesitylene or 1,3-dimethoxybenzene with disulfur dichloride or sulfur dichloride as well as the oxidation of dithiols.The synthesis of bi-and trimacrocyclic compounds is based on the reaction of 1,3,5-tris(mercaptoalkyl)benzenes with tris(bromoalkyl)-methanes or l,3,5-tris[4-(mercaptomethyl)phenyl]-benzene with 1,3,5-tris-[4-(bromomethyl)phenyl] benzene.Some methods for the synthesis of sulfur-containing macroheterocycles containing silicon, tellurium, or iron are considered.The structures of the sulfur-containing macroheterocycles are discussed using the results of X-ray diffraction, H NMR, IR, and UV spectroscopy as well as their electroconductive and magnetic properties.

Macroheterocycles中科院分区

大类学科 分区 小类学科 分区 Top期刊 综述期刊
化学 4区 CHEMISTRY, MULTIDISCIPLINARY 化学综合 4区

JCR分区

JCR分区等级 JCR所属学科 分区 影响因子
Q4 CHEMISTRY, MULTIDISCIPLINARY Q4 1.418

Macroheterocycles影响因子

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